On this day 250 years ago in Philadelphia, Peyton Randolph died at age 54 of a stroke while having dinner with his cousin and fellow delegate to the Continental Congress, Thomas Jefferson. Although little known today, Randolph was the first President of the Continental Congress and the President of the first three Virginia Conventions. He was to that point the most prominent leader of the American Revolution. The next day his fellow Delegate Richard Henry Lee wrote to George Washington that

American liberty lost a powerful Advocate, and human nature a sincere friend.

Source: https://daybydayamerica.com/day-by-day/year-1775/october-22-1775/; https://kamcpherson.substack.com/p/death-of-peyton-randolph